Can commodity products detect which pixel you’re looking at on a screen?

For a number of years, I’ve wanted a system that eliminates mouse pointer devices. In my imaginary system, there are hotkeys bound to left & right mouse clicks, and what gets clicked is whatever you’re looking at.

When I’ve looked at this before, the tech field tends to suffer in granularity and/or physical limitations, like needing to limit gross head movements. Most products talk about what they can do, but avoid talking about their limitations. It can be hard to find out what devices are capable of - accuracy, working with corrective eyewear, speed, head movement, software (OS) support, etc. Many products are geared at research, leading me to believe the tech isn’t there yet.

Anyone have, or used a device that would be able to replace a mouse?